What is UPNEEQ?

UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is a eyedrop used to treat acquired blepharoptosis (low-lying lids) in adults.


How Do I Apply Upneeq?

Apply Upneeq to your affected eye(s) in 2 easy steps

Step 1: Cut open foil wrapper and remove single-use vial

Step 2: Apply one drop of Upneeq in each affected eye as directed, once a day

  • Do not let the tip of the vial touch your eye or any other surface
  • Vials should not be re-used after opening and should be thrown away after applying drop(s)
  • If you wear contact lenses, remove them before applying Upneeq eyedrops
    • You may put them back in 15 minutes after applying Upneeq
  • If more than one topical ophthalmic drug is being used, the drugs should be administered at least 15 minutes between applications

Upneeq should only be used as directed

  • Upneeq is designed to only be applied as an eyedrop
  • Each vial contains enough Upneeq solution to allow for one drop in each affected eye
  • The solution should never be swallowed or ingested in any other way
  • Storage requirements: Upneeq should be stored at 68°F-77°F (20°C-25°C) and should be protected from excessive heat
  • Keep out of reach of children




 What warnings and precautions are associated with UPNEEQ?